Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Aug;24(8):1586-1587.
doi: 10.3201/eid2408.180105.

Autochthonous Hepatitis E during Pregnancy, France

Elise Bouthry, Alexandra Benachi, Alexandre J Vivanti, Emmanuelle Letamendia, Christelle Vauloup-Fellous, Anne-Marie Roque-Afonso
Case Reports

Autochthonous Hepatitis E during Pregnancy, France

Elise Bouthry et al. Emerg Infect Dis. 2018 Aug.

Abstract

Acute hepatitis E virus infections occurred during the third trimester in 2 pregnant women in France who sought treatment with nonspecific symptoms or asymptomatic elevation of liver enzymes. Infection cleared quickly in both women. We detected no hepatitis E RNA in 1 newborn's feces at 3 weeks of age.

Keywords: France; HEV; genotype 3; hepatitis E; mother-to-child transmission; pregnancy; viruses.

PubMed Disclaimer

Figures

Figure
Figure
Relationship of HEV RNA and alanine aminotransferase to gestation and delivery time for 2 pregnant women, case-patient 1 (A) and case-patient 2 (B), France. Upper limit of normal for ALT values is 40 U/L. HEV RNA was quantified by a commercial real-time reverse transcription PCR assay targeting open reading frame 2/3. ALT, alanine aminotransferase; HEV, hepatitis E virus (Ceeram, La Chapelle sur Erdre, France).
See this image and copyright information in PMC

References

    1. Rein DB, Stevens GA, Theaker J, Wittenborn JS, Wiersma ST. The global burden of hepatitis E virus genotypes 1 and 2 in 2005. Hepatology. 2012;55:988–97. 10.1002/hep.25505 - DOI - PubMed
    1. Pérez-Gracia MT, Suay-García B, Mateos-Lindemann ML. Hepatitis E and pregnancy: current state. Rev Med Virol. 2017;27:e1929. 10.1002/rmv.1929 - DOI - PubMed
    1. Kamar N, Izopet J, Pavio N, Aggarwal R, Labrique A, Wedemeyer H, et al. Hepatitis E virus infection. Nat Rev Dis Primers. 2017;3:17086. 10.1038/nrdp.2017.86 - DOI - PubMed
    1. Anty R, Ollier L, Péron JM, Nicand E, Cannavo I, Bongain A, et al. First case report of an acute genotype 3 hepatitis E infected pregnant woman living in South-Eastern France. J Clin Virol. 2012;54:76–8. 10.1016/j.jcv.2012.01.016 - DOI - PubMed
    1. Tabatabai J, Wenzel JJ, Soboletzki M, Flux C, Navid MH, Schnitzler P. First case report of an acute hepatitis E subgenotype 3c infection during pregnancy in Germany. J Clin Virol. 2014;61:170–2. 10.1016/j.jcv.2014.06.008 - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources