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Review
. 2018 Jul 17;23(7):1751.
doi: 10.3390/molecules23071751.

Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion

Mehdi Sharifi-Rad  1 , Patrick Valere Tsouh Fokou  2 , Farukh Sharopov  3 , Miquel Martorell  4 , Adedayo Oluwaseun Ademiluyi  5 , Jovana Rajkovic  6 , Bahare Salehi  7   8 , Natália Martins  9   10 , Marcello Iriti  11 , Javad Sharifi-Rad  12   13
Affiliations
Review

Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion

Mehdi Sharifi-Rad et al. Molecules. .

Abstract

In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.

Keywords: Helicobacter pylori; bioactive phytochemicals; gastric cancer; herbal remedies; peptic ulcer; traditional healing systems.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Structure of some phytochemicals evaluated as antiulcer agents.
Figure 1
Figure 1
Structure of some phytochemicals evaluated as antiulcer agents.
See this image and copyright information in PMC

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