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Book

Finasteride

Patrick M. Zito  1 , Karlyle G. Bistas  2 , Preeti Patel, Kirin Syed
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Finasteride

Patrick M. Zito et al.
Free Books & Documents

Excerpt

Finasteride, an FDA-approved therapeutic agent, plays a pivotal role in managing benign prostate hyperplasia and androgenic alopecia (male pattern hair loss) in men. Through its competitive inhibition of 5-alpha-reductase (types II and III isoenzymes), finasteride impedes the conversion of testosterone to dihydrotestosterone (DHT), addressing the underlying pathophysiology of these conditions. This activity discusses finasteride's diverse applications, extending beyond its primary indications to treat hyperandrogenism-associated manifestations, such as hirsutism.

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Conflict of interest statement

Disclosure: Patrick Zito declares no relevant financial relationships with ineligible companies.

Disclosure: Karlyle Bistas declares no relevant financial relationships with ineligible companies.

Disclosure: Preeti Patel declares no relevant financial relationships with ineligible companies.

Disclosure: Kirin Syed declares no relevant financial relationships with ineligible companies.

References

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    1. Martin KA, Anderson RR, Chang RJ, Ehrmann DA, Lobo RA, Murad MH, Pugeat MM, Rosenfield RL. Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018 Apr 01;103(4):1233-1257. - PubMed
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