Getting a Taste for Parasites in the Gut
- PMID: 30021142
- DOI: 10.1016/j.immuni.2018.07.002
Getting a Taste for Parasites in the Gut
Abstract
How type 2 immune responses are initiated is obscure. Nadjsombati et al. (2018), along with two other studies (Lei et al., 2018; Schneider et al., 2018), show that tuft cells can initiate type 2 responses by recognizing the metabolite succinate produced by intestinal parasites.
Copyright © 2018. Published by Elsevier Inc.
Comment on
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Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit.Immunity. 2018 Jul 17;49(1):33-41.e7. doi: 10.1016/j.immuni.2018.06.016. Immunity. 2018. PMID: 30021144 Free PMC article.
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