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Review
. 2018 Jun;10(Suppl 16):S1864-S1870.
doi: 10.21037/jtd.2018.03.151.

Catheter-based alternative treatment for early-stage lung cancer with a high-risk for morbidity

Ze-Rui Zhao  1 , Rainbow W H Lau  1 , Calvin S H Ng  1
Affiliations
Review

Catheter-based alternative treatment for early-stage lung cancer with a high-risk for morbidity

Ze-Rui Zhao et al. J Thorac Dis. 2018 Jun.

Abstract

The mainstream treatment modality for early stage non-small cell lung cancer (NSCLC) is surgery; however, many patients are deemed inoperable and warrant alternative therapeutic options. Several minimally invasive catheter-based therapies are emerging as viable alternatives. In this review, we evaluate the outcomes from radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation (CRA) and photodynamic therapy (PDT) for early-stage lung cancer. Novel technical developments have allowed for endobronchial thermal ablation to be conducted in a hybrid theatre setting, which may optimize treatment outcomes and minimise treatment-related complications.

Keywords: Thermal therapy; alternative treatment; early stage; non-small cell lung cancer (NSCLC).

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Conflict of interest statement

Conflicts of Interest: CS Ng has an electromagnetic navigational bronchoscopy system SuperDimension Version 7 on loan from Medtronic. ZR Zhao and RW Lau have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Hybrid theatre dyna-CT axial, coronal, sagittal and 3D-reconstructed views of electromagnetic navigation bronchoscopy catheter and needle within the 1 cm right upper lobe peripheral tumour. Use of such real-time imaging to guide and confirm successful endobronchial ablation will be highly valuable.
See this image and copyright information in PMC

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