Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Nov;39(11):1857-1860.
doi: 10.1007/s10072-018-3504-1. Epub 2018 Jul 21.

Predictors of survival in spinocerebellar ataxia type 2 population from Southern Italy

Antonella Antenora  1 , Dario Bruzzese  2 , Maria Lieto  1 , Alessandro Roca  1 , Maria Teresa Florio  1 , Silvio Peluso  1 , Francesco Saccà  1 , Giuseppe De Michele  1 , Filippo Maria Santorelli  3 , Alessandro Filla  4
Affiliations

Predictors of survival in spinocerebellar ataxia type 2 population from Southern Italy

Antonella Antenora et al. Neurol Sci. 2018 Nov.

Abstract

One hundred-eighteen spinocerebellar ataxia type 2 patients from 35 distinct families personally observed between 1973 and 2016 were retrospectively reviewed. The time point of data collection was 1 January 2017. Thirty-one patients were confined to wheelchair. The median time to wheelchair was 21 years (95% CI, 17.5-24.6). Thirty-seven patients were deceased. The median time to death was 25 years (95% CI, 22.9-27.1). CAG repeat number and ataxia score at first visit influenced the time to wheelchair and death.

Keywords: Ataxia scale; CAG repeats; SCA2; Survival.

PubMed Disclaimer

References

    1. Arch Neurol. 2004 May;61(5):727-33 - PubMed
    1. Lancet Neurol. 2018 Apr;17(4):327-334 - PubMed
    1. Brain. 1998 Apr;121 ( Pt 4):589-600 - PubMed
    1. J Neurol. 1990 Oct;237(6):345-51 - PubMed
    1. Neuroepidemiology. 2014;42(3):174-83 - PubMed