Advances in Urologic Imaging: Prostate-Specific Membrane Antigen Ligand PET Imaging

Abstract

Radiolabeled prostate-specific membrane antigen PET (PSMA PET) is emerging as an important modality for imaging prostate cancer (PCa). Promising clinical experience has led to increasing number of studies exploring the role of PSMA PET in different aspects of PCa including primary detection, risk stratification, targeted biopsy, initial staging, restaging at biochemical recurrence, biologic characterization, treatment response assessment and prognostication. PSMA PET may prove an important disease biomarker, expand our understanding of the pathogenesis and pave the way for personalized management of PCa.

Keywords: PET; PSMA PET; PSMA PET/CT; Prostate cancer; Prostate-specific membrane antigen.