Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Jun;10(Suppl 15):S1790-S1793.
doi: 10.21037/jtd.2017.10.124.

The momentum of HeartMate 3: a novel active magnetically levitated centrifugal left ventricular assist device (LVAD)

Affiliations
Review

The momentum of HeartMate 3: a novel active magnetically levitated centrifugal left ventricular assist device (LVAD)

Anamika Chatterjee et al. J Thorac Dis. 2018 Jun.

Abstract

Left ventricular assist devices (LVADs) are emerging as the treatment of choice for advanced heart failure due to the dearth of healthy donor hearts for cardiac transplantation. The HeartMate 3 LVAD is a novel centrifugal pump which was developed to provide hemodynamic support in heart failure patients, either as a bridge to transplant (BTT), myocardial recovery, or as destination therapy (DT). Technological and clinical advancements have led to optimized hemocompatibility and development of less invasive surgical procedures for the implantation of this pump. The worldwide first implantation of the HeartMate 3 was performed by Prof. Schmitto and his team at Hannover Medical School, Germany in 2014, paving the way for subsequent surgical developments. This article summarizes the advanced technological and clinical aspects of the HeartMate 3 and outlines future technical developments for safe and effective treatment of advanced heart failure.

Keywords: Centrifugal pump; HeartMate 3; left ventricular assist device (LVAD).

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: JD Schmitto receives consultation fees from Abbott. The other authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Pump technology of HeartMate 3. The HeartMate 3 is a novel centrifugal flow pump with an axial flux motor along with active magnetic mounting. The motor technology of this LVAD is bearingless and consists of a single unit which combines the rotor, drive, as well as magnetic bearing functions. LVAD, left ventricular assist device.

References

    1. Schmitto JD, Hanke JS, Rojas SV, et al. First implantation in man of a new magnetically levitated left ventricular assist device (HeartMate III). J Heart Lung Transplant 2015;34:858-60. 10.1016/j.healun.2015.03.001 - DOI - PubMed
    1. WHO. NCD mortality and morbidity [Internet]. WHO. [cited 2016 Oct 24]. Available online: http://www.who.int/gho/ncd/mortality_morbidity/en/
    1. Fang J, Mensah GA, Croft JB, et al. Heart failure-related hospitalization in the U.S., 1979 to 2004. J Am Coll Cardiol 2008;52:428-34. 10.1016/j.jacc.2008.03.061 - DOI - PubMed
    1. Ashton RC, Goldstein DJ, Rose EA, et al. Duration of left ventricular assist device support affects transplant survival. J Heart Lung Transplant 1996;15:1151-7. - PubMed
    1. Allen GS, Murray KD, Olsen DB. The importance of pulsatile and nonpulsatile flow in the design of blood pumps. Artif Organs 1997;21:922-8. 10.1111/j.1525-1594.1997.tb00252.x - DOI - PubMed

LinkOut - more resources