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Review
. 2018 Aug;36(3):585-601.
doi: 10.1016/j.emc.2018.04.014.

Anticoagulation Reversal

Erica M Simon  1 , Matthew J Streitz  2 , Daniel J Sessions  3 , Colin G Kaide  4
Affiliations
Review

Anticoagulation Reversal

Erica M Simon et al. Emerg Med Clin North Am. 2018 Aug.

Abstract

Today a variety of anticoagulants and antiplatelet agents are available on the market. Given the propensity for bleeding among patients prescribed these medications, the emergency medicine physician must be equipped with a working knowledge of hemostasis, and anticoagulant and antiplatelet reversal. This article reviews strategies to address bleeding complications occurring secondary to warfarin, low-molecular-weight heparin, and direct oral anticoagulant therapy.

Keywords: Anticoagulant reversal; Heparin; Idarucizumab; Novel oral anticoagulants; Prothrombin complex concentrate; Warfarin.

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