Uterus Transplantation: The Ethics of Using Deceased Versus Living Donors
- PMID: 30040550
- PMCID: PMC6296249
- DOI: 10.1080/15265161.2018.1478018
Uterus Transplantation: The Ethics of Using Deceased Versus Living Donors
Abstract
Research teams have made considerable progress in treating absolute uterine factor infertility through uterus transplantation, though studies have differed on the choice of either deceased or living donors. While researchers continue to analyze the medical feasibility of both approaches, little attention has been paid to the ethics of using deceased versus living donors as well as the protections that must be in place for each. Both types of uterus donation also pose unique regulatory challenges, including how to allocate donated organs; whether the donor / donor's family has any rights to the uterus and resulting child; how to manage contact between the donor / donor's family, recipient, and resulting child; and how to track outcomes moving forward.
Keywords: informed consent; organ transplantation; rationing/resource allocation; regulatory issues; reproductive technologies.
Conflict of interest statement
Conflicts of Interest – none
Comment in
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On Gender and Reproductive Decision-Making in Uterine Transplantation.Am J Bioeth. 2018 Jul;18(7):3-5. doi: 10.1080/15265161.2018.1489655. Am J Bioeth. 2018. PMID: 30040551 No abstract available.
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Toward the Ethical Allocation of Uterine Transplants.Am J Bioeth. 2018 Jul;18(7):16-17. doi: 10.1080/15265161.2018.1478039. Am J Bioeth. 2018. PMID: 30040555 No abstract available.
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The Purported Procurement Priority of Lifesaving Organs Over Non-Lifesaving Organs: Uterus Transplants and the Ethical Importance of Potential Lives.Am J Bioeth. 2018 Jul;18(7):25-26. doi: 10.1080/15265161.2018.1478032. Am J Bioeth. 2018. PMID: 30040563 No abstract available.
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UTx With Deceased Donors Also Places Risks and Burdens on Third Parties.Am J Bioeth. 2018 Jul;18(7):22-24. doi: 10.1080/15265161.2018.1478029. Am J Bioeth. 2018. PMID: 30040566 No abstract available.
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Experience and Ethics at the "Cutting Edge": Lessons From Maternal-Fetal Surgery for Uterine Transplantation.Am J Bioeth. 2018 Jul;18(7):29-31. doi: 10.1080/15265161.2018.1478041. Am J Bioeth. 2018. PMID: 30040570 No abstract available.
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A Woman in Full.Am J Bioeth. 2018 Jul;18(7):32-34. doi: 10.1080/15265161.2018.1478028. Am J Bioeth. 2018. PMID: 30040572 No abstract available.
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Uterus Transplantation: A Step Too Far.Am J Bioeth. 2018 Jul;18(7):36-37. doi: 10.1080/15265161.2018.1478027. Am J Bioeth. 2018. PMID: 30040573 No abstract available.
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Living Donation, Listing, and Prioritization in Uterus Transplantation.Am J Bioeth. 2018 Jul;18(7):20-22. doi: 10.1080/15265161.2018.1478026. Am J Bioeth. 2018. PMID: 30040574 No abstract available.
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Allocating Uterus Transplants-Who Gets to Be a Gestational Mother?Am J Bioeth. 2018 Jul;18(7):38-39. doi: 10.1080/15265161.2018.1478025. Am J Bioeth. 2018. PMID: 30040575 No abstract available.
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How Do You Donate Life When People Are Not Dying: Transplants in the Age of Autonomous Vehicles.Am J Bioeth. 2018 Jul;18(7):27-29. doi: 10.1080/15265161.2018.1478024. Am J Bioeth. 2018. PMID: 30040577 No abstract available.
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"Whole Again": Why Are Penile Transplants Less Controversial Than Uterine?Am J Bioeth. 2018 Jul;18(7):34-35. doi: 10.1080/15265161.2018.1478044. Am J Bioeth. 2018. PMID: 30040581 No abstract available.
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Deceased Donation in Uterus Transplantation Trials: Novelty, Consent, and Surrogate Decision Making.Am J Bioeth. 2018 Jul;18(7):18-20. doi: 10.1080/15265161.2018.1478043. Am J Bioeth. 2018. PMID: 30040583 No abstract available.
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Uterus Transplantation: Response to Open Peer Commentaries on the Ethics of Using Deceased Versus Living Donors.Am J Bioeth. 2018 Sep;18(9):W6-W8. doi: 10.1080/15265161.2018.1502836. Am J Bioeth. 2018. PMID: 30235090 Free PMC article. No abstract available.
References
-
- Ahn E, Bai S, Song C, Kim J, Jeong K, Kim S, Lee J, Kwon J, and Park K. 2002. “Effect of hysterectomy on conserved ovarian function.” Yonsei Medical Journal 43(1): 53–58. - PubMed
-
- Akar ME, Ozkan O, Aydinuraz B, Dirican K, Cincik M, Mendilcioglu I, Simsek M, Gunseren F, Kocak H, Ciftcioglu A, Gecici O, and Ozkan O. 2013. “Clinical pregnancy after uterus transplantation.” Fertility & Sterility 100(5): 1358–1363. - PubMed
-
- Arora K, and Blake V. 2014. “Uterus transplantation: Ethical and regulatory challenges.” Journal of Medical Ethics 40: 396–400. - PubMed
-
- Atay V, Ceyhan T, Baser I, Gungor S, Goktolga U, and Muhcu M. 2007. “Hysterectomy with preservation of both ovaries does not result in premature ovarian failure.” Journal of International Medical Research 35(3): 416–421. - PubMed
-
- Bayefsky M, and Berkman B. 2016. “The ethics of allocating uterine transplants.” Cambridge Quarterly of Healthcare Ethics 25: 350–365. - PubMed
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