Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Practice Guideline
. 2018 Aug;67(2):292-310.
doi: 10.1097/MPG.0000000000002036.

Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis-An Evidence-based Consensus Guideline From the European Crohn's and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition

Dan Turner  1 , Frank M Ruemmele  2 , Esther Orlanski-Meyer  1 , Anne M Griffiths  3 , Javier Martin de Carpi  4 , Jiri Bronsky  5 , Gabor Veres  6 , Marina Aloi  7 , Caterina Strisciuglio  8 , Christian P Braegger  9 , Amit Assa  10 , Claudio Romano  11 , Séamus Hussey  12 , Michael Stanton  13 , Mikko Pakarinen  14 , Lissy de Ridder  15 , Konstantinos H Katsanos  16 , Nick Croft  17 , Víctor Manuel Navas-López  18 , David C Wilson  19 , Sally Lawrence  20 , Richard K Russell  21
Affiliations
Free article
Practice Guideline

Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis-An Evidence-based Consensus Guideline From the European Crohn's and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition

Dan Turner et al. J Pediatr Gastroenterol Nutr. 2018 Aug.
Free article

Abstract

Background and aim: Acute severe colitis (ASC) is one of the few emergencies in pediatric gastroenterology. Tight monitoring and timely medical and surgical interventions may improve outcomes and minimize morbidity and mortality. We aimed to standardize daily treatment of ASC in children through detailed recommendations and practice points which are based on a systematic review of the literature and consensus of experts.

Methods: These guidelines are a joint effort of the European Crohn's and Colitis Organization (ECCO) and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). Fifteen predefined questions were addressed by working subgroups. An iterative consensus process, including 2 face-to-face meetings, was followed by voting of the national representatives of ECCO and all members of the Paediatric Inflammatory Bowel Disease (IBD) Porto group of ESPGHAN (43 voting experts).

Results: A total of 24 recommendations and 43 practice points were endorsed with a consensus rate of at least 91% regarding diagnosis, monitoring, and management of ASC in children. A summary flowchart is presented based on daily scoring of the Paediatric Ulcerative Colitis Activity Index. Several topics have been altered since the previous 2011 guidelines and from those published in adults.

Discussion: These guidelines standardize the management of ASC in children in an attempt to optimize outcomes of this intensive clinical scenario.

PubMed Disclaimer

Publication types

Supplementary concepts