Review
doi: 10.1002/JLB.4RI0418-151R.
Epub 2018 Jul 25.
The interplay between neutrophils and microbiota in cancer
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- PMID: 30044897
- DOI: 10.1002/JLB.4RI0418-151R
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Review
The interplay between neutrophils and microbiota in cancer
J Leukoc Biol.
2018 Oct.
Abstract
The role of the microbiota in many diseases including cancer has gained increasing attention. Paired with this is our expanding appreciation for the heterogeneity of the neutrophil compartment regarding surface marker expression and functionality. In this review, we will discuss the influence of the microbiota on granulopoiesis and consequent activity of neutrophils in cancer. As evidence for this microbiota-neutrophil-cancer axis builds, it exposes new therapeutic targets to improve a cancer patient's outcome.
Keywords: TAN; cancer; granulopoiesis; microbiota; neutrophils.
©2018 Society for Leukocyte Biology.
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