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Case Reports
. 2019 Jan;41(1):37-39.
doi: 10.1097/DAD.0000000000001222.

Pityriasis Rubra Pilaris With Extensive Follicular Acantholysis Resembling Pemphigus Vulgaris: A Case Report

Mohammed T Lilo  1 , Shaofeng Yan  1 , Michael Shane Chapman  2 , Konstantinos Linos  1
Affiliations
Case Reports

Pityriasis Rubra Pilaris With Extensive Follicular Acantholysis Resembling Pemphigus Vulgaris: A Case Report

Mohammed T Lilo et al. Am J Dermatopathol. 2019 Jan.

Abstract

Pityriasis rubra pilaris (PRP) is a rare, chronic, heterogeneous, papulosquamous inflammatory dermatosis of unknown etiology. Although erythematous scaly patches characterize the classic presentation of PRP, a broad range of clinical presentations has been reported. Histologically, PRP is characterized by psoriasiform acanthosis with alternating orthokeratosis and parakeratosis and rarely small acantholytic foci. In this article, we report a patient who presented with diffuse erythroderma and extensive acantholysis mimicking pemphigus vulgaris histologically.

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