Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Affiliations

¹ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA.
² Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
³ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA. amandinova@partners.org.
⁴ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. amandinova@partners.org.
⁵ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. stuart_schreiber@harvard.edu.
⁶ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA. swlee@partners.org.
⁷ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. swlee@partners.org.

PMID: 30046103
PMCID: PMC6148382
DOI: 10.1038/s41586-018-0284-y

Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Lakshmi Raj et al. Nature. 2018 Sep.

. 2018 Sep;561(7723):420.

doi: 10.1038/s41586-018-0284-y.

Authors

Affiliations

¹ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA.
² Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
³ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA. amandinova@partners.org.
⁴ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. amandinova@partners.org.
⁵ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. stuart_schreiber@harvard.edu.
⁶ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA. swlee@partners.org.
⁷ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. swlee@partners.org.

PMID: 30046103
PMCID: PMC6148382
DOI: 10.1038/s41586-018-0284-y

Abstract

This Letter is being retracted owing to issues with Fig. 1d and Supplementary Fig. 31b, and the unavailability of original data for these figures that raise concerns regarding the integrity of the figures. Nature published two previous corrections related to this Letter^1,2. These issues in aggregate undermine the confidence in the integrity of this study. Authors Michael Foley, Monica Schenone, Nicola J. Tolliday, Todd R. Golub, Steven A. Carr, Alykhan F. Shamji, Andrew M. Stern and Stuart L. Schreiber agree with the Retraction. Authors Lakshmi Raj, Takao Ide, Aditi U. Gurkar, Anna Mandinova and Sam W. Lee disagree with the Retraction. Author Xiaoyu Li did not respond.

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Retraction of

Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Raj L, et al. Nature. 2011 Jul 13;475(7355):231-4. doi: 10.1038/nature10167. Nature. 2011. Retraction in: Nature. 2018 Sep;561(7723):420. doi: 10.1038/s41586-018-0284-y. PMID: 21753854 Free PMC article. Retracted.

References

1. Raj L et al. Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature 481, 534 (2012). - PubMed
1. Raj L et al. Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature 526, 596 (2015). - PubMed

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Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Affiliations

Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Authors

Affiliations

Abstract

Retraction of

References

Publication types

LinkOut - more resources

Full Text Sources

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