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Review
. 2018 Nov;19(11):613-623.
doi: 10.2459/JCM.0000000000000700.

Right heart dysfunction: from pathophysiologic insights to therapeutic options: a translational overview

Valentina Mercurio  1 , Alberto Palazzuoli  2 , Michele Correale  3 , Carlo Lombardi  4 , Andrea Passantino  5 , Alice Ravera  4 , Gaetano Ruocco  2 , Edoardo Sciatti  4 , Marco Triggiani  4 , Rocco Lagioia  5 , Domenico Scrutinio  5 , Carlo G Tocchetti  1 , Savina Nodari  4
Affiliations
Review

Right heart dysfunction: from pathophysiologic insights to therapeutic options: a translational overview

Valentina Mercurio et al. J Cardiovasc Med (Hagerstown). 2018 Nov.

Abstract

: The right ventricle has become increasingly studied in cardiovascular research. In this article, we describe specific pathophysiological characteristics of the right ventricle, with special focus on functional and molecular modifications as well as therapeutic strategies in right ventricular dysfunction, underlining the differences with the left ventricle. Then we analyze the main imaging modalities to assess right ventricular function in different clinical settings. Finally, we acknowledge main therapeutic advances for treatment of right heart diseases.

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