ISCHEMIA: A Search for clarity and why we may not find it
- PMID: 30048826
- PMCID: PMC6393742
- DOI: 10.1016/j.ahj.2018.03.031
ISCHEMIA: A Search for clarity and why we may not find it
Comment on
-
International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial: Rationale and design.Am Heart J. 2018 Jul;201:124-135. doi: 10.1016/j.ahj.2018.04.011. Epub 2018 Apr 21. Am Heart J. 2018. PMID: 29778671 Free PMC article. Review.
References
-
- Boden WE, O’Rourke RA, Teo KK, et al. Optimal Medical Therapy with or without PCI for Stable Coronary Disease. N Engl J Med 2007;356(15):1503–16. - PubMed
-
- Al-Lamee R, Thompson D, Dehbi H-M, et al. Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial. Lancet 2018;391(10115):31–40. - PubMed
-
- Shaw LJ, Berman DS, Maron DJ, et al. Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy. Circulation 2008;117(10):1283–91. - PubMed
-
- De Bruyne B, Fearon WF, Pijls NHJ, et al. Fractional Flow Reserve-Guided PCI for Stable Coronary Artery Disease. N Engl J Med 2014;371:1208–17. [Available from: http://www.nejm.org/doi/full/10.1056/NEJMoa1408758]. - DOI - PubMed
-
- Rajkumar CA, Nijjer SS, Cole GD, et al. Moving the Goalposts Into Unblinded Territory: The Larger Lessons of DEFER and FAME 2 and Their Implications for Shifting End Points in ISCHEMIA. Circ Cardiovasc Qual Outcomes 2018;11(3), e004665. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
