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Review
. 2018 Jul 19:5:75-80.
doi: 10.2147/JHC.S145450. eCollection 2018.

Hepatocellular cancer pain: impact and management challenges

Nathaniel Christian-Miller  1 , Catherine Frenette  2
Affiliations
Review

Hepatocellular cancer pain: impact and management challenges

Nathaniel Christian-Miller et al. J Hepatocell Carcinoma. .

Abstract

Hepatocellular carcinoma (HCC) remains the most common primary liver malignancy. Pain comprises one of the most pervasive and troubling symptoms of HCC and may have severely negative effects on patient's quality of life. Furthermore, because HCC frequently arises in the setting of cirrhosis, treating pain related to this malignancy poses a clinical challenge. This article summarizes manifestations of hepatocellular cancer pain, common obstacles to treatment, and practical HCC pain management.

Keywords: analgesic; cirrhosis; health-related QOL; hepatocellular carcinoma; loco-regional therapy; opioid.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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