Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies
- PMID: 3005173
- PMCID: PMC260994
- DOI: 10.1128/iai.51.3.961-963.1986
Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies
Abstract
Mice injected with either of two monoclonal antibodies specific for the O polysaccharide of Brucella abortus prior to challenge infection had viable counts in spleens and livers significantly below those in control groups 1 and 4 weeks later. Two monoclonal antibodies specific for the porin of B. abortus failed to confer protection.
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