Comment
doi: 10.1016/j.cell.2018.07.014.
Changing the Guard at a Prostate Cancer SNP
Affiliations
- PMID: 30053422
- DOI: 10.1016/j.cell.2018.07.014
Item in Clipboard
Comment
Changing the Guard at a Prostate Cancer SNP
Cell.
.
Free article
Abstract
The molecular underpinnings of a prostate-cancer-associated SNP are investigated in a pair of papers in this issue of Cell. Together, Gao et al. and Hua et al. paint a picture of competition between transcription factors that, in turn, toggle the function of a regulatory region from a promoter to an enhancer and induce a switch in noncoding RNA isoforms.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
-
Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus.Cell. 2018 Jul 26;174(3):576-589.e18. doi: 10.1016/j.cell.2018.06.003. Epub 2018 Jul 19. Cell. 2018. PMID: 30033361 Free PMC article.
-
Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.Cell. 2018 Jul 26;174(3):564-575.e18. doi: 10.1016/j.cell.2018.06.014. Epub 2018 Jul 19. Cell. 2018. PMID: 30033362
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
