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Case Reports
. 2018 Jun 29;11(2):436-441.
doi: 10.1159/000490527. eCollection 2018 May-Aug.

Leser-Trélat Sign Presenting in a Patient with Relapsing Mycosis Fungoides

Fahad Alsaif  1 , Fares Abdulmajed Alkhayal  2 , Rawan Aldahash  2 , Ahmed Alhumaidi  3
Affiliations
Case Reports

Leser-Trélat Sign Presenting in a Patient with Relapsing Mycosis Fungoides

Fahad Alsaif et al. Case Rep Oncol. .

Abstract

The Leser-Trélat sign is a rare sign of some malignant tumors and is characterized by the sudden appearance of seborrheic keratosis in association with an underlying malignancy. We describe a 60-year-old Saudi man with mycosis fungoides (MF) who developed numerous, rapidly growing, seborrheic keratoses on his face and back. To the best of our knowledge, this is the first reported case of MF with the Leser-Trélat sign from Saudi Arabia.

Keywords: Leser-Trélat sign; Mycosis fungoides; Paraneoplastic; Seborrheic keratoses.

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Figures

Fig. 1
Fig. 1
Clinical picture of the eruption of the seborrheic keratosis over face.
Fig. 2
Fig. 2
Clinical picture of the eruption of the seborrheic keratosis over back and multiple lesions of MF.
Fig. 3
Fig. 3
Upper back lesion reveals acanthosis, pigmented keratinocytes, and pseudohorn cysts consistent with seborrheic keratosis. H/E stain. ×100.
Fig. 4
Fig. 4
Biopsy from right lower back exhibits atypical lymphocytes in epidermis with papillary dermal fibrosis. H/E stain. ×400.
See this image and copyright information in PMC

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