Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jul;11(7):32-35.
Epub 2018 Jul 1.

Androgenetic Alopecia Treatment in Asian Men

Affiliations

Androgenetic Alopecia Treatment in Asian Men

Yohei Tanaka et al. J Clin Aesthet Dermatol. 2018 Jul.

Abstract

Background: Androgenetic alopecia (AGA) is a common form of hair loss in Asian men. Although AGA is often regarded as a relatively minor dermatological condition, hair loss can impact self-image and is a main cause for anxiety and depression in some men. We have treated patients with AGA for seven years. Objective: The goal of this study was to evaluate the effectiveness of our combination therapy in Asian men with AGA. Participants: Between the years 2011 and 2017, 18,918 male patients were treated in our center. Our combination therapy consists of oral finasteride once daily, oral and topical minoxidil twice daily, and an injectable treatment of lidocaine and an AGA treatment solution comprising minoxidil, arginine, aspartic acid, caffeine, copper tripeptide, lysine, niacin, panthenol, propanediol, propylen glycol, retinyl palmitate, pyridoxine, sodium hyaluronate, and ubiquinone once monthly for more than six months. Measurements: Digital photographs were taken pre- and post-treatment, and patient assessments were recorded after six and 12 months post-treatment. Results: Significant improvement was observed in all patients in the digital photographs. Ninety-six and 80 percent of the patients reported satisfaction with the results of the treatment after six and 12 months post-treatment. Minor complications were observed in 802 (4.2%) patients, characterized by slight pain and bleeding due to injection, swelling, dizziness, itching, and erythema of the scalp. Slight pain was reported in 651 patients (3.4%), and slight bleeding was reported in 56 patients (0.3%). Sexual dysfunctions were uncommon. These minor complications resolved spontaneously. No treatment-related adverse events were observed. Conclusion: A combination of these therapeutic options offers safe and highly efficacious treatment for AGA with minimal complications.

Keywords: Androgenetic alopecia (AGA); Combination therapy; Finasteride; Hair loss; Minoxidil.

PubMed Disclaimer

Conflict of interest statement

FUNDING:No funding was provided. DISCLOSURES:The authors have no conflicts of interest relevant to the content of this article.

Figures

FIGURE 1.
FIGURE 1.
Representative photographs of hair regrowth, before and after treatment—21-year-old man (A) pretreatment and (B) 6 months after treatment; 33-year-old man (C) pretreatment and (D) 6 months after treatment
FIGURE 1.
FIGURE 1.
Representative photographs of hair regrowth, before and after treatment—21-year-old man (A) pretreatment and (B) 6 months after treatment; 33-year-old man (C) pretreatment and (D) 6 months after treatment
FIGURE 1.
FIGURE 1.
Representative photographs of hair regrowth, before and after treatment—21-year-old man (A) pretreatment and (B) 6 months after treatment; 33-year-old man (C) pretreatment and (D) 6 months after treatment
FIGURE 1.
FIGURE 1.
Representative photographs of hair regrowth, before and after treatment—21-year-old man (A) pretreatment and (B) 6 months after treatment; 33-year-old man (C) pretreatment and (D) 6 months after treatment
FIGURE 2.
FIGURE 2.
Representative photographs of hair regrowth before and after treatment—42-year-old man (A)pretreatment and (B) 6 months after treatment; 55-year-old man (C) pretreatment and (D) 6 months after treatment
FIGURE 2.
FIGURE 2.
Representative photographs of hair regrowth before and after treatment—42-year-old man (A)pretreatment and (B) 6 months after treatment; 55-year-old man (C) pretreatment and (D) 6 months after treatment
FIGURE 2.
FIGURE 2.
Representative photographs of hair regrowth before and after treatment—42-year-old man (A)pretreatment and (B) 6 months after treatment; 55-year-old man (C) pretreatment and (D) 6 months after treatment
FIGURE 2.
FIGURE 2.
Representative photographs of hair regrowth before and after treatment—42-year-old man (A)pretreatment and (B) 6 months after treatment; 55-year-old man (C) pretreatment and (D) 6 months after treatment
FIGURE 3.
FIGURE 3.
Subjective satisfaction with treatment results after 6 and 12 months post-treatment

References

    1. Jang WS, Son IP, Yeo IK, et al. The annual changes of clinical manifestation of androgenetic alopecia clinic in Korean males and females: a outpatient-based study. Ann Dermatol. 2013;25:181–188. - PMC - PubMed
    1. Choi J, Jun M, Lee S, et al. The association between exercise and androgenetic alopecia: a survey-based study. Ann Dermatol. 2017;29:513–516. - PMC - PubMed
    1. Yang CC, Hsieh FN, Lin LY, et al. Higher body mass index is associated with greater severity of alopecia in men with male-pattern androgenetic alopecia in Taiwan: a cross-sectional study. J Am Acad Dermatol. 2014;70:297–302.e1. - PubMed
    1. Sinclair R, Torkamani N, Jones L. Androgenetic alopecia: new insights into the pathogenesis and mechanism of hair loss. Version 1. F1000Res. 2015;4:585. (F1000 Faculty Rev) Published online 2015 Aug 19. - PMC - PubMed
    1. Di Loreto C, La Marra F, Mazzon G, et al. Immunohistochemical evaluation of androgen receptor and nerve structure density in human prepuce from patients with persistent sexual side effects after finasteride use for androgenetic alopecia. PLoS One. 2014;9:e100237. - PMC - PubMed

LinkOut - more resources