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. 1986 Feb;319(6055):640-6.
doi: 10.1038/319640a0.

Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter

Y Noma, P Sideras, T Naito, S Bergstedt-Lindquist, C Azuma, E Severinson, T Tanabe, T Kinashi, F Matsuda, Y Yaoita, et al.

Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter

Y Noma et al. Nature. 1986 Feb.

Abstract

Complementary DNA encoding the IgG1 induction factor, the first lymphokine directed to B lymphocytes, from a murine T-cell line has been cloned using a new strategy. The putative primary amino-acid sequence was deduced from the nucleotide sequence determined. The lymphokine synthesized by the direction of this cloned cDNA has many other functions, such as production of B-cell growth factor-1 and induction of Ia on B cells.

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