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Review
. 2018 Aug 1;29(15):1779-1785.
doi: 10.1091/mbc.E18-04-0260.

Toward mapping the human body at a cellular resolution

Ananda L Roy  1 , Richard S Conroy  1
Affiliations
Review

Toward mapping the human body at a cellular resolution

Ananda L Roy et al. Mol Biol Cell. .

Abstract

The adult human body is composed of nearly 37 trillion cells, each with potentially unique molecular characteristics. This Perspective describes some of the challenges and opportunities faced in mapping the molecular characteristics of these cells in specific regions of the body and highlights areas for international collaboration toward the broader goal of comprehensively mapping the human body with cellular resolution.

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References

    1. Ackerman MJ. (2017). The Visible Human Project: from body to bits. IEEE Pulse , 39–41. - PubMed
    1. Ajami B, Samusik N, Wieghofer P, Ho PP, Crotti A, Bjornson Z, Prinz M, Fantl WJ, Nolan GP, Steinman L. (2018). Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models. Nat Neurosci , 541–551. - PMC - PubMed
    1. Angelo M, Bendall SC, Finck R, Hale MB, Hitzman C, Borowsky AD, Levenson RM, Lowe JB, Liu SD, Zhao S, et al (2014). Multiplexed ion beam imaging of human breast tumors. Nat Med , 436–442. - PMC - PubMed
    1. Ardini-Poleske ME, Clark RF, Ansong C, Carson JP, Corley RA, Deutsch GH, Hagood JS, Kaminski N, Mariani TJ, Potter SS, et al (2017). LungMAP: The Molecular Atlas of Lung Development Program. Am J Physiol Lung Cell Mol Physiol , L733–L740. - PMC - PubMed
    1. Bandyopadhyay S, Fisher DAC, Malkova O, Oh ST. (2017). Analysis of signaling networks at the single-cell level using mass cytometry. Methods Mol Biol , 371–392. - PubMed

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