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. 1977 Mar;52(3):245-7.
doi: 10.1136/adc.52.3.245.

Serial studies of numbers of circulating T and B lymphocytes in children with acute lymphoblastic leukaemia

Serial studies of numbers of circulating T and B lymphocytes in children with acute lymphoblastic leukaemia

M M Reid et al. Arch Dis Child. 1977 Mar.

Abstract

Serial studies of numbers of circulating T and B lymphocytes at monthly intervals in children with acute lymphoblastic leukaemia showed a marked fall in the number of B cells, relatively greater than that of T cells, early in the course of maintenance chemotherapy and immediately after a course of cranial irradiation. The fall in the number of B cell is not a consequence of long-term chemotherapy, and is possibly related to a specific event such as cranial irradiation.

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