Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jun;30(2):95-97.
doi: 10.5455/msm.2018.30.95-97.

Mortality and Functional Disability of Poststroke Delirium

Zikrija Dostovic  1 , Dzevdet Smajlovic  1 , Omer C Ibrahimagic  1 , Adnan Dostovic  2
Affiliations

Mortality and Functional Disability of Poststroke Delirium

Zikrija Dostovic et al. Mater Sociomed. 2018 Jun.

Abstract

Introduction: Small number of studies have evaluated the mortality and the degree of functional disability of post-stroke delirium, and our aim was to determine that.

Patients and methods: Comprehensive neuropsychological assessments were performed within the first week of stroke onset, at hospital discharge, and followed-up for 3, 6 and 12 months after stroke. We used diagnostic tools such as Glasgow Coma Scale, Delirium Rating Scale, National Institutes of Health Stroke Scale and Mini-Mental State.

Results: Delirious patients had a significantly higher mortality (p = 0.0005). As opposed to the type of stroke mortality was higher after ischemic (p = 0.0005). The patients without delirium had significantly better cumulative survival during the first year after stroke (p = 0.0005). Delirious patients aged ≥65 years had a significantly lower cumulative survival during the first year after stroke (p = 0.0005). In relation to the type of stroke delirious patients with ischemic had a significantly lower cumulative survival during the first year after stroke (p = 0.0005). Delirious patients had a greater degree of functional impairment at discharge (p = 0.01), three (p = 0.01), six months (p = 0.01) and one year (p = 0.01) after stroke.

Conclusion: Delirious patients have a significantly higher mortality, lower cumulative survival and a greater degree of functional disability in the first year after stroke.

Keywords: delirium; functional disability; mortality; stroke.

PubMed Disclaimer

References

    1. Sheng AZ, Shen Q, Cordato D, Zhang YY, Yin Chan DK. Delirium within three days of stroke in a cohort of elderly patients. J Am Geriatr Soc. 2006;54(8):1192–1198. - PubMed
    1. Gustafson Y, Olsson T, Asplund K, Hägg E. Acute confusional state (delirium) soon after stroke is associated with hypercortisolism. Cerebrovasc Dis. 1993;3:33–38.
    1. Henon H, Lebert F, Durieu I, Godefroy O, Lucas C, Pasquier F, Leys D. Confusional state in stroke. Relation to preexisting dementia, patient characteristics, and outcome. Stroke. 1999;30:773–779. - PubMed
    1. Teasdale G, Jennett B. Assessment of coma and impaired consciousness. Lance. 1974:81–84. - PubMed
    1. Trzepacz PT. Update on the neuropathogenesis of delirium. Dement Geriatr Cogn Disord. 1999;10:330–334. - PubMed

LinkOut - more resources