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Review
. 2018 Apr-Jun;26(2):68-76.
doi: 10.4103/JMU.JMU_1_17. Epub 2018 May 7.

A Review of Suspension-Scattered Particles Used in Blood-Mimicking Fluid for Doppler Ultrasound Imaging

Affiliations
Review

A Review of Suspension-Scattered Particles Used in Blood-Mimicking Fluid for Doppler Ultrasound Imaging

Ammar A Oglat et al. J Med Ultrasound. 2018 Apr-Jun.

Abstract

Doppler ultrasound imaging system description and calibration need blood-mimicking fluids (BMFs) for the test target of medical ultrasound diagnostic tools, with known interior features and acoustic and physical properties of this fluid (BMF). Physical and acoustical properties determined in the International Electrotechnical Commission (IEC) standard are specified as constant values, the materials used in the BMF preparation should have values similar to the IEC standard values. However, BMF is ready-made commercially from a field of medical usage, which may not be appropriate in the layout of ultrasound system or for an estimate of novel imaging mechanism. It is often eligible to have the capability to make sound properties and mimic blood arrangement for specific applications. In this review, sufficient BMF materials, liquids, and measures are described which have been generated by utilizing diverse operation mechanism and materials that have sculptured a range of biological systems.

Keywords: Acoustical properties; blood-mimicking fluid; physical properties; suspension scatter particle materials.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Erythrocytes showing – a^ : One cell and b^ : a gross cell. (b) Orgasol™ or Nylon particles showing – a^: solo particle and b^: an aggregate of particles. Small divisions equal 2.2 μ[38]
Figure 2
Figure 2
Regular flow from blood-mimicking fluid with relative backscatter plotted versus nylon particle ratio with different particle diameters of 5, 10, and 20 μm[43]

References

    1. Ramnarine KV, Nassiri DK, Hoskins PR, Lubbers J. Validation of a new blood-mimicking fluid for use in Doppler flow test objects. Ultrasound Med Biol. 1998;24:451–9. - PubMed
    1. Lubbers J. Application of a new blood-mimicking fluid in a flow Doppler test object. Eur J Ultrasound. 1999;9:267–76. - PubMed
    1. Liu Y, Maruvada S, King RL, Herman BA, Wear KA. Development and characterization of a blood mimicking fluid for high intensity focused ultrasound. J Acoust Soc Am. 2008;124:1803–10. - PubMed
    1. Law YF, Johnston KW, Routh HF, Cobbold RS. On the design and evaluation of a steady flow model for Doppler ultrasound studies. Ultrasound Med Biol. 1989;15:505–16. - PubMed
    1. Chien S, Usami S, Dellenback RJ, Gregersen MI, Nanninga LB, Guest MM, et al. Blood viscosity: Influence of erythrocyte aggregation. Science. 1967;157:829–31. - PubMed