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Clinical Trial
. 2018 Nov;37(11):e264-e268.
doi: 10.1097/INF.0000000000002152.

Tenofovir Disoproxil Fumarate Use during Pregnancy and Infant Bone Health: the Tenofovir in Pregnancy Pilot Study

Athena P Kourtis  1 , Jeffrey Wiener  1 , Liming Wang  2 , Bo Fan  3 , John A Shepherd  3 , Lili Chen  4 , Wei Liu  5 , Colin Shepard  2 , Linhong Wang  6 , Ailin Wang  6 , Marc Bulterys  2
Affiliations
Clinical Trial

Tenofovir Disoproxil Fumarate Use during Pregnancy and Infant Bone Health: the Tenofovir in Pregnancy Pilot Study

Athena P Kourtis et al. Pediatr Infect Dis J. 2018 Nov.

Abstract

The effects of maternal tenofovir use on infant bone mineral content (BMC) and bone mineral density (BMD) were evaluated in a pilot study of HIV/Hepatitis B-coinfected pregnant women in China. BMD and BMC were assessed at age 6 months of life in 14 tenofovir-exposed and 13 unexposed infants. Trends toward lower BMC and BMD were observed in infants exposed to maternal tenofovir but were not statistically significant.

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