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Review
. 2018 Aug;36(3):675-685.
doi: 10.1016/j.ncl.2018.04.015. Epub 2018 Jun 18.

Paraneoplastic Neurologic Syndromes

Myrna R Rosenfeld  1 , Josep Dalmau  2
Affiliations
Review

Paraneoplastic Neurologic Syndromes

Myrna R Rosenfeld et al. Neurol Clin. 2018 Aug.

Abstract

Paraneoplastic neurologic syndromes (PNS) are mostly immune-mediated disorders that occur in patients with cancer. Because the same neurologic syndromes may occur without a cancer association it is important to know the likelihood of PNS, which is based in part on the syndrome and the patient's demographics and risk factors for cancer. The presence of specific antineuronal antibodies can facilitate the diagnosis and suggest treatment strategies. Although some PNS are rarely responsive to therapies, other disorders are highly treatment responsive.

Keywords: Antibody; Autoimmune encephalitis; Cancer; Neurologic; Paraneoplastic.

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