Lesson of the month 2: Blunt abdominal trauma: atypical presentation of phaeochromocytoma
- PMID: 30072564
- PMCID: PMC6334037
- DOI: 10.7861/clinmedicine.18-4-345
Lesson of the month 2: Blunt abdominal trauma: atypical presentation of phaeochromocytoma
Abstract
A 26-year-old man presented following blunt abdominal trauma to a regional major trauma centre for emergency embolisation of a retroperitoneal bleed from a presumed renal laceration. Imaging had also revealed a large right suprarenal mass. Embolisation resulted in a hypertensive crisis raising the suspicion of a metabolically active adrenal tumour. The course was further complicated by the development of ischaemic bowel requiring emergency laparotomy. Intraoperatively he became haemodynamically unstable from an actively haemorrhaging lesion. Emergency laparotomy and adrenalectomy was performed as a life-saving procedure. Histology confirmed a phaeochromocytoma. The patient made a gradual recovery and was discharged home with no sequelae. Definitive management of phaeochromocytoma is surgical resection which requires prolonged preoperative optimisation with alpha receptor blockers to adequately control blood pressure and prevent hypertensive crises. Parenteral alpha receptor blockers, such as phentolamine, are optimal treatment for intraoperative hypertensive emergencies, yet they are currently not available in the UK.
Keywords: Phaeochromocytoma; abdominal trauma; interventional radiology.
© Royal College of Physicians 2018. All rights reserved.
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Comment in
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Established endocrine practice.Clin Med (Lond). 2019 Jan;19(1):91. doi: 10.7861/clinmedicine.19-1-91a. Clin Med (Lond). 2019. PMID: 30651266 Free PMC article. No abstract available.
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Mechanical circulatory support such as extracorporeal membrane oxygenation is indicated in phaeochromocytoma crisis with sustained hypotension.Clin Med (Lond). 2019 Jan;19(1):91-92. doi: 10.7861/clinmedicine.19-1-91b. Clin Med (Lond). 2019. PMID: 30651267 Free PMC article. No abstract available.
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Response.Clin Med (Lond). 2019 Jan;19(1):92. doi: 10.7861/clinmedicine.19-1-92. Clin Med (Lond). 2019. PMID: 30651268 Free PMC article. No abstract available.
References
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- Lenders JW. Duh QY. Eisenhofer G, et al. Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2014. pp. 1915–42. - PubMed
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- Scholten A. Cisco RM. Vriens MR, et al. Pheochromocytoma crisis is not a surgical emergency. J Clin Endocrinol Metab. 2013;98:581–91. - PubMed
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