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Comment
. 2018 Aug 3;3(26):eaau0112.
doi: 10.1126/sciimmunol.aau0112.

Neutrophil ghosts worsen asthma

Marsha Wills-Karp  1
Affiliations
Comment

Neutrophil ghosts worsen asthma

Marsha Wills-Karp. Sci Immunol. .

Abstract

Neutrophil cytoplasts are linked to amplification of T helper 17-mediated inflammation and severe asthma.

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Comment on

  • Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.
    Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators. Krishnamoorthy N, et al. Sci Immunol. 2018 Aug 3;3(26):eaao4747. doi: 10.1126/sciimmunol.aao4747. Sci Immunol. 2018. PMID: 30076281 Free PMC article.