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Book

Hyperviscosity Syndrome

Alexis Perez Rogers, Molly Estes
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Free Books & Documents
Book

Hyperviscosity Syndrome

Alexis Perez Rogers et al.
Free Books & Documents

Excerpt

Hyperviscosity syndrome (HVS) is an oncologic emergency that classically presents with the triad of neurological deficits, visual changes, and mucosal bleeding. Elevated blood viscosity results from either red blood cell shape deformity or a pathological increase in serum proteins, red blood cells, white blood cells, or platelets. The most common cause of HVS is Waldenstrom macroglobulinemia; therefore, the term HVS is typically used to describe increased serum proteins. Management consists of supportive care with intravenous fluids, plasmapheresis, and treatment of the underlying hematological condition.

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Conflict of interest statement

Disclosure: Alexis Perez Rogers declares no relevant financial relationships with ineligible companies.

Disclosure: Molly Estes declares no relevant financial relationships with ineligible companies.

References

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