Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Kasabach-Merritt Syndrome

Deirdre Lewis, Ruben Vaidya  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Kasabach-Merritt Syndrome

Deirdre Lewis et al.
Free Books & Documents

Excerpt

Kasabach-Merritt phenomenon (KMP), first described in 1940, is a rare but life-threatening coagulopathy of infancy which presents with thrombocytopenia, microangiopathic hemolytic anemia, and consumptive coagulopathy in the setting of a rapidly enlarging vascular tumor. It is exclusively associated with the vascular tumors kaposiform hemangioendothelioma (KHE) and tufted angioma (TA), which exist along the same neoplastic spectrum. Treatment includes supportive therapy and management of the underlying tumor.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Deirdre Lewis declares no relevant financial relationships with ineligible companies.

Disclosure: Ruben Vaidya declares no relevant financial relationships with ineligible companies.

References

    1. Gözdaşoğlu S. Kasabach-Merritt Syndrome in an Adult: A Comment. Turk J Haematol. 2019 Feb 07;36(1):52-53. - PMC - PubMed
    1. Ji Y, Chen S, Li L, Yang K, Xia C, Li L, Yang G, Kong F, Lu G, Liu X. Kaposiform hemangioendothelioma without cutaneous involvement. J Cancer Res Clin Oncol. 2018 Dec;144(12):2475-2484. - PMC - PubMed
    1. Ji Y, Chen S, Yang K, Xia C, Peng S. Development of Kasabach-Merritt phenomenon following vaccination: More than a coincidence? J Dermatol. 2018 Oct;45(10):1203-1206. - PubMed
    1. Schmid I, Klenk AK, Sparber-Sauer M, Koscielniak E, Maxwell R, Häberle B. Kaposiform hemangioendothelioma in children: a benign vascular tumor with multiple treatment options. World J Pediatr. 2018 Aug;14(4):322-329. - PubMed
    1. Mahajan P, Margolin J, Iacobas I. Kasabach-Merritt Phenomenon: Classic Presentation and Management Options. Clin Med Insights Blood Disord. 2017;10:1179545X17699849. - PMC - PubMed

Publication types

LinkOut - more resources