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Review
. 2018 Jul:4:1-11.
doi: 10.1200/JGO.18.00041.

Burden of Disease, Early Diagnosis, and Treatment of Merkel Cell Carcinoma in Latin America

Rafael A Schmerling  1 , Jose G Casas  1 , Gabriela Cinat  1 , Fabio Ernesto Grosso Ospina  1 , Luiza E B P Kassuga  1 , Jorge Luis Martinez Tlahuel  1 , Luis Daniel Mazzuoccolo  1
Affiliations
Review

Burden of Disease, Early Diagnosis, and Treatment of Merkel Cell Carcinoma in Latin America

Rafael A Schmerling et al. J Glob Oncol. 2018 Jul.
No abstract available

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Figures

Fig 1
Fig 1
Solitary, painless, and firm, with red-violet or red-blue appearance.
Fig 2
Fig 2
Dermoscopic reveals sparse and irregular linear vessels and milky red areas.
Fig 3
Fig 3
Pathology of Merkel cell carcinoma: proliferation of uniform, small, round, blue undifferentiated cells with spherical or oval nuclei and scant cytoplasm. (Left) Sheets of small cells extending throughout the dermis (hematoxylin and eosin [H&E]). (Right) Small, round, blue undifferentiated cells at a higher magnification (H&E).
Fig 4
Fig 4
Immunohystochemistry of Merkel cell carcinoma. Dot-like positivity image for cytokeratin 20 (immunoperoxidase stain).
See this image and copyright information in PMC

References

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    1. Fitzgerald TL, Dennis S, Kachare SD, et al. Dramatic increase in the incidence and mortality from Merkel cell carcinoma in the United States. Am Surg. 2015;81:802–806. - PubMed
    1. Lemos BD, Storer BE, Iyer JG, et al. Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: Analysis of 5823 cases as the basis of the first consensus staging system. J Am Acad Dermatol. 2010;63:751–761. - PMC - PubMed
    1. Girschik J, Thorn K, Beer TW, et al. Merkel cell carcinoma in Western Australia: A population-based study of incidence and survival. Br J Dermatol. 2011;165:1051–1057. - PubMed
    1. Mills LA, Durrani AJ, Watson JD. Merkel cell carcinoma in South East Scotland, 1993-2003. Surgeon. 2006;4:133–138. - PubMed

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