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. 2018 Aug 7;15(8):e1002632.
doi: 10.1371/journal.pmed.1002632. eCollection 2018 Aug.

Choices in vaccine trial design in epidemics of emerging infections

Affiliations

Choices in vaccine trial design in epidemics of emerging infections

Rebecca Kahn et al. PLoS Med. .

Abstract

In a Policy Forum, Marc Lipsitch and colleagues discuss trial design issues in infectious disease outbreaks.

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Conflict of interest statement

I have read the journal’s policy and the authors of this manuscript have the following competing interests: ML has received consulting fees/honoraria from Pfizer, Merck, Affinivax, and Antigen Discovery and research grants from Pfizer and PATH Vaccine Solutions.

References

    1. Brende B, Farrar J, Gashumba D, Moedas C, Mundel T, Shiozaki Y, et al. CEPI—a new global R&D organisation for epidemic preparedness and response. Lancet. 2017;389: 233–235. 10.1016/S0140-6736(17)30131-9 - DOI - PMC - PubMed
    1. WHO. Blueprint for R&D preparedness and response to public health emergencies due to highly infectious pathogens. WHO workshop on prioritization of pathogens report. 2015.
    1. National Academy of Sciences Engineering and Medicine. Integrating clinical research into epidemic response: the Ebola experience. National Academies Press; 2017. - PubMed
    1. Cohen J, Kupferschmidt K. Tough choices ahead in Ebola vaccine trials. ScienceMag. 2014; 1–8.
    1. Cohen J. Issues continue to dog the testing of Ebola drugs and vaccines. ScienceMag. 2014.

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