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Comment
. 2018 Aug 6;28(15):R842-R845.
doi: 10.1016/j.cub.2018.06.067.

Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

Ian G Ganley  1
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Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

Ian G Ganley. Curr Biol. .
Free article

Abstract

It is crucial to remove dysfunctional mitochondria and peroxisomes to prevent cellular damage. Recent work suggests that under basal conditions USP30, a deubiquitinating enzyme, works to ensure that both of these organelles are only turned over at the right time.

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