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. 2018 Aug 7;320(5):502-504.
doi: 10.1001/jama.2018.6933.

Opioid Overdose After Surgical Discharge

Karim S Ladha  1 , Joshua J Gagne  1 , Elisabetta Patorno  1 , Krista F Huybrechts  1 , James P Rathmell  2 , Shirley V Wang  1 , Brian T Bateman  1
Affiliations

Opioid Overdose After Surgical Discharge

Karim S Ladha et al. JAMA. .

Abstract

This pharmacoepidemiology study uses commercial claims database data to describe the rate of opioid overdose 1 to 3 months after surgical discharge by dose and procedure from 2004 to 2015.

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Conflict of interest statement

Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Gagne reported grants from Eli Lilly and Novartis Pharmaceuticals and personal fees from Aetion and Optum. Dr Wang reported being principal investigator on grants from Novartis, Boehringer Ingelheim, and Johnson & Johnson to her institution and consulting for Aetion. No other disclosures were reported.

Figures

Figure.
Figure.. Rate of Postoperative Opioid Overdose in Entire Cohort and Stratified by Preoperative Daily Morphine Equivalent Dose
Error bars indicate 95% CIs. aOverall opioid overdose rate per 100 000 operations within 30 days of hospital discharge.
See this image and copyright information in PMC

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