Large deletions induced by Cas9 cleavage

Fatwa Adikusuma^{1

2

3

4}, Sandra Piltz^{1

2

4}, Mark A Corbett², Michelle Turvey⁵, Shaun R McColl¹, Karla J Helbig⁶, Michael R Beard¹, James Hughes¹, Richard T Pomerantz⁷, Paul Q Thomas^{8

9

10}

Affiliations

¹ School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
² Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.
³ Centre for Biomedical Research (CEBIOR), Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
⁴ South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
⁵ Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
⁶ School of Life Sciences, La Trobe University, Melbourne, Victoria, Australia.
⁷ Fels Institute for Cancer Research, Department of Medical Genetics and Molecular Biochemistry, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.
⁸ School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia. paul.thomas@adelaide.edu.au.
⁹ Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia. paul.thomas@adelaide.edu.au.
¹⁰ South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. paul.thomas@adelaide.edu.au.

Comment

Fatwa Adikusuma et al. Nature. 2018 Aug.

. 2018 Aug;560(7717):E8-E9.

doi: 10.1038/s41586-018-0380-z. Epub 2018 Aug 8.

¹ School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
² Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.
³ Centre for Biomedical Research (CEBIOR), Faculty of Medicine, Diponegoro University, Semarang, Indonesia.
⁴ South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
⁵ Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
⁶ School of Life Sciences, La Trobe University, Melbourne, Victoria, Australia.
⁷ Fels Institute for Cancer Research, Department of Medical Genetics and Molecular Biochemistry, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.
⁸ School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia. paul.thomas@adelaide.edu.au.
⁹ Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia. paul.thomas@adelaide.edu.au.
¹⁰ South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. paul.thomas@adelaide.edu.au.

No abstract available

Comment on

Correction of a pathogenic gene mutation in human embryos.
Ma H, Marti-Gutierrez N, Park SW, Wu J, Lee Y, Suzuki K, Koski A, Ji D, Hayama T, Ahmed R, Darby H, Van Dyken C, Li Y, Kang E, Park AR, Kim D, Kim ST, Gong J, Gu Y, Xu X, Battaglia D, Krieg SA, Lee DM, Wu DH, Wolf DP, Heitner SB, Belmonte JCI, Amato P, Kim JS, Kaul S, Mitalipov S. Ma H, et al. Nature. 2017 Aug 24;548(7668):413-419. doi: 10.1038/nature23305. Epub 2017 Aug 2. Nature. 2017. PMID: 28783728