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Review
. 2018 Aug 7;24(29):3204-3221.
doi: 10.3748/wjg.v24.i29.3204.

Helicobacter pylori and extragastric diseases: A review

Antonietta Gerarda Gravina  1 , Rocco Maurizio Zagari  2 , Cristiana De Musis  1 , Lorenzo Romano  1 , Carmelina Loguercio  1 , Marco Romano  3
Affiliations
Review

Helicobacter pylori and extragastric diseases: A review

Antonietta Gerarda Gravina et al. World J Gastroenterol. .

Abstract

Helicobacter pylori (H. pylori) infection is very common and affects approximately half of the world population. It causes gastric diseases, but some authors have reported an association of H. pylori infection with other systemic manifestations beginning in 1994. The list of potential effects of H. pylori outside the stomach includes a number of extragastric manifestations and we focused on neurological, dermatological, hematologic, ocular, cardiovascular, metabolic, allergic, and hepatobiliary diseases. This review discusses these important reported manifestations that are not related to the gastrointestinal tract.

Keywords: Allergic diseases; Cardiovascular diseases; Dermatological diseases; Extragastric disease; Helicobacter pylori; Hematologic diseases; Hepatobiliary diseases; Metabolic diseases; Neurological diseases; Ocular diseases.

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Conflict of interest statement

Conflict-of-interest statement: The authors have no conflicts of interest and no financial support.

Figures

Figure 1
Figure 1
Hematologic diseases associated to Helicobacter pylori infection.
See this image and copyright information in PMC

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