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Review
. 2018 Aug 1;9(4):706-715.
doi: 10.14336/AD.2017.0928. eCollection 2018 Aug.

The Prevalence of Mild Cognitive Impairment in China: A Systematic Review

Jiang Xue #  1 , Jiarui Li #  2 , Jiaming Liang  1 , Shulin Chen  1
Affiliations
Review

The Prevalence of Mild Cognitive Impairment in China: A Systematic Review

Jiang Xue et al. Aging Dis. .

Abstract

The aim of this study was to analyze the prevalence of mild cognitive impairment (MCI) among the aging population (60 years of age and above) in China. Epidemiological investigations on MCI in online Chinese journals were identified manually using the CQVIP, CNKI, and Wanfang databases. Articles from journals published in English were identified using PubMed and Web of Science. Original studies that included prevalence surveys of MCI were selected. Forty-eight relevant studies were included in the analysis, covering 22 provinces in China. Our results showed that the pooled prevalence of MCI in the older Chinese population was 14.71% (95% confidence interval [CI], 14.50-14.92%). The prevalence was 16.72% (95% CI, 15.68-17.71%) in clinical samples vs. 14.61% (95% CI, 14.40-14.83%) in nonclinical samples (χ2=16.60, P<0.01), and 15.20% (95% CI, 14.91-15.49%) in screened samples vs. 14.16% (95% CI, 13.85-14.46%) in diagnosed samples (χ2=22.11, P<0.01). People of older age, of female sex, or living in rural areas or western China were associated with a higher prevalence of MCI. The prevalence of MCI was high in Chinese older adults, and even higher in those who were older, female, or living in rural areas or western China. Future studies are recommended to address the prevalence of MCI in the other 12 provinces of China. Furthermore, diagnostic assessments should be included in the identification of MCI.

Keywords: China; mild cognitive impairment; prevalence; systematic review.

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Figures

Figure 1.
Figure 1.
Map of the prevalence of mild cognitive impairment in China.
Figure 2.
Figure 2.
Fitted curves of the prevalence of MCI in subgroups.
See this image and copyright information in PMC

References

    1. Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, et al. (2001). Current concepts in mild cognitive impairment. Arch Neurol, 58: 1985-1992 - PubMed
    1. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E (1999). Mild cognitive impairment: clinical characterization and outcome. Arch Neurol, 56: 303-308 - PubMed
    1. Petersen RC (2011). Clinical practice. Mild cognitive impairment. N Engl J Med, 364: 2227-2234 - PubMed
    1. Gauthier S, Reisberg B, Zaudig M, Petersen RC, Ritchie K, Broich K, et al. (2006). Mild cognitive impairment. Lancet, 367: 1262-1270 - PubMed
    1. Burns A, Zaudig M (2002). Mild cognitive impairment in older people. Lancet, 360: 1963-1965 - PubMed

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