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Comment
. 2018 Sep;8(9):OF2.
doi: 10.1158/2159-8290.CD-NB2018-106. Epub 2018 Aug 9.

CRISPR Causes Unexpected Genomic Damage

No authors listed
Comment

CRISPR Causes Unexpected Genomic Damage

No authors listed. Cancer Discov. 2018 Sep.

Abstract

A study in four cell lines concludes that CRISPR/Cas9 editing causes unanticipated genomic alterations, including large deletions, translocations, and insertions. Some of these changes could be the first hits that cause cells to eventually become neoplastic.

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