Suppression of monocyte inflammatory and coagulopathy responses in HIV infection

Reena Rajasuriar^{1

2

3}, Anna C Hearps^{4

5}, Suzanne M Crowe^{4

6}, Joshua J Anzinger⁷, Clovis S Palmer^{4

6

8}

Affiliations

¹ Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
² Centre of Excellence for Research in AIDS (CERiA), University of Malaya, Kuala Lumpur, Malaysia.
³ Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
⁴ Life Sciences, Burnet Institute, Melbourne, VIC, Australia.
⁵ Department of Infectious Diseases, Monash University, Melbourne, VIC, Australia.
⁶ School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
⁷ Department of Microbiology, University of the West Indies, Mona, Kingston, Jamaica.
⁸ Department of Microbiology and Immunology, University of Melbourne, Melbourne, VIC, Australia.

Editorial

Reena Rajasuriar et al. Ann Transl Med. 2018 Jul.

. 2018 Jul;6(13):277.

doi: 10.21037/atm.2018.06.20.

Reena Rajasuriar^{1

2

3}, Anna C Hearps^{4

5}, Suzanne M Crowe^{4

6}, Joshua J Anzinger⁷, Clovis S Palmer^{4

6

8}

¹ Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
² Centre of Excellence for Research in AIDS (CERiA), University of Malaya, Kuala Lumpur, Malaysia.
³ Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
⁴ Life Sciences, Burnet Institute, Melbourne, VIC, Australia.
⁵ Department of Infectious Diseases, Monash University, Melbourne, VIC, Australia.
⁶ School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
⁷ Department of Microbiology, University of the West Indies, Mona, Kingston, Jamaica.
⁸ Department of Microbiology and Immunology, University of Melbourne, Melbourne, VIC, Australia.

No abstract available

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy.
Schechter ME, Andrade BB, He T, Richter GH, Tosh KW, Policicchio BB, Singh A, Raehtz KD, Sheikh V, Ma D, Brocca-Cofano E, Apetrei C, Tracy R, Ribeiro RM, Sher A, Francischetti IMB, Pandrea I, Sereti I. Schechter ME, et al. Sci Transl Med. 2017 Aug 30;9(405):eaam5441. doi: 10.1126/scitranslmed.aam5441. Sci Transl Med. 2017. PMID: 28855397 Free PMC article.

1. Smit M, Brinkman K, Geerlings S, et al. Future challenges for clinical care of an ageing population infected with HIV: a modelling study. Lancet Infect Dis 2015;15:810-8. 10.1016/S1473-3099(15)00056-0 - DOI - PMC - PubMed
1. Puhr R, Kumarasamy N, Ly PS, et al. HIV and Aging: Demographic Change in the Asia-Pacific Region. J Acquir Immune Defic Syndr 2017;74:e146-8. 10.1097/QAI.0000000000001258 - DOI - PMC - PubMed
1. Antiretroviral Therapy Cohort Collaboration Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies. Lancet HIV 2017;4:e349-56. 10.1016/S2352-3018(17)30066-8 - DOI - PMC - PubMed
1. Teeraananchai S, Kerr SJ, Amin J, et al. Life expectancy of HIV-positive people after starting combination antiretroviral therapy: a meta-analysis. HIV Med 2017;18:256-66. 10.1111/hiv.12421 - DOI - PubMed
1. Guaraldi G, Palella FJ., Jr Clinical implications of aging with HIV infection: perspectives and the future medical care agenda. AIDS 2017;31 Suppl 2:S129-35. 10.1097/QAD.0000000000001478 - DOI - PubMed