Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2018 Nov 13;32(17):2633-2635.
doi: 10.1097/QAD.0000000000001983.

Increasing prevalence of self-reported HIV preexposure prophylaxis use in published surveys: a systematic review and meta-analysis

Emiko Kamitani  1   2 , Megan E Wichser  3 , Adebukola H Adegbite  3 , Mary M Mullins  1 , Wayne D Johnson  1 , Pierre-Cedric Crouch  4 , Theresa Ann Sipe  1
Affiliations
Meta-Analysis

Increasing prevalence of self-reported HIV preexposure prophylaxis use in published surveys: a systematic review and meta-analysis

Emiko Kamitani et al. AIDS. .

Abstract

: When combining results from all published surveys, about one in nine global study participants (10.7%) reported ever using preexposure prophylaxis (PrEP) by 2017, a significant increase since US FDA approval in 2012 [odds ratio (OR) = 1.6/year, P < 0.00001]. Moreover, nearly one in six US-based study participants (17.3%) and nearly one in four MSM who met the Centers for Disease Control and Prevention's PrEP indications (24.5%) reported ever using PrEP by 2016. The odds of reporting PrEP use are approximately doubling each year (OR = 1.8/year, P < 0.00001; OR = 2.0/year, P < 0.00001).

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
Pooled prevalence of self-reported preexposure prophylaxis use in study participants: global vs. USA overall vs. MSM meeting CDC’s PrEP indications in the USA (N = 72).
See this image and copyright information in PMC

Comment in

References

    1. Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010; 363:2587–2599. - PMC - PubMed
    1. Liu AY, Cohen SE, Vittinghoff E, Anderson PL, Doblecki-Lewis S, Bacon O, et al. HIV pre-exposure prophylaxis integrated with municipal and community based sexual health services. JAMA Intern Med 2016; 176:75–84. - PMC - PubMed
    1. McCormack S, Dunn DT, Desai M, Dolling DI, Gafos M, Gilson R, et al. Preexposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. Lancet; 387:53–60. - PMC - PubMed
    1. Volk JE, Marcus JL, Phengrasamy T, Blechinger D, Nguyen DP, Follansbee S, et al. No new HIV infections with increasing use of HIV preexposure prophylaxis in a clinical practice setting. Clin Infect Dis 2015; 61:1601–1603. - PMC - PubMed
    1. Centers for Disease Control and Prevention. Preexposure prophylaxis for the prevention of HIV infection in the United States-2014: a clinical practice guideline Atlanta, GA: Centers for Disease Control and Prevention; 2014.