Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Aug 8;6(3):73.
doi: 10.3390/diseases6030073.

Wine: An Aspiring Agent in Promoting Longevity and Preventing Chronic Diseases

Affiliations
Review

Wine: An Aspiring Agent in Promoting Longevity and Preventing Chronic Diseases

Eleni Pavlidou et al. Diseases. .

Abstract

Introduction: Moderate wine consumption is a characteristic of the Mediterranean diet. Studies around the world have shown a beneficial effect of moderate alcohol intake, especially wine, on health. This review aims to critically summarise the most recent studies that investigate the beneficial effects of moderate wine intake on human health.

Methods: The PubMed database was comprehensively searched to identify trials published from 2013 to 2018 that investigated the association between moderate wine consumption and health.

Results: The most recent studies confirm the valuable role of moderate wine consumption, especially red wine, in the prevention and treatment of chronic diseases such as cardiovascular disease, metabolic syndrome, cognitive decline, depression, and cancer. In the meantime, recent studies also highlight the beneficial role of red wine against oxidative stress and in favour of desirable gut bacteria. The beneficial role of red wine has been attributed to its phytochemical compounds, as highlighted by clinical trials, where the effect of red wine has been compared to white wine, non-alcoholic wine, other alcoholic drinks, and water.

Conclusions: Moderate wine intake, at 1⁻2 glasses per day as part of the Mediterranean diet, has been positively associated with human health promotion, disease prevention, and disease prognosis.

Keywords: cardiovascular disease; dementia; diet; health; vine; wine.

PubMed Disclaimer

Conflict of interest statement

Christina Tryfonos is a PhD candidate and is financially supported by YPATIA fellowship provided by the University of the Aegean. All other authors declare that there are no conflicts of interest.

References

    1. Trichopoulou A., Naska A., Orfanos P., Trichopoulos D. Mediterranean Diet in Relation to Body Mass Index and Waist-to-Hip Ratio: The Greek European Prospective Investigation into Cancer and Nutrition Study. Am. J. Clin. Nutr. 2005;82:935–940. doi: 10.1093/ajcn/82.5.935. - DOI - PubMed
    1. Gotsis E., Anagnostis P., Mariolis A., Vlachou A., Katsiki N., Karagiannis A. Health Benefits of the Mediterranean Diet: An Update of Research over the Last 5 Years. Angiology. 2015;66:304–318. doi: 10.1177/0003319714532169. - DOI - PubMed
    1. Schwingshackl L., Hoffmann G. Adherence to Mediterranean Diet and Risk of Cancer: An Updated Systematic Review and Meta-Analysis of Observational Studies. Cancer Med. 2015;4:1933–1947. doi: 10.1002/cam4.539. - DOI - PMC - PubMed
    1. Schwingshackl L., Missbach B., Konig J., Hoffmann G. Adherence to a Mediterranean Diet and Risk of Diabetes: A Systematic Review and Meta-Analysis. Public Health Nutr. 2015;18:1292–1299. doi: 10.1017/S1368980014001542. - DOI - PMC - PubMed
    1. Widmer R.J., Flammer A.J., Lerman L.O., Lerman A. The Mediterranean Diet, Its Components, and Cardiovascular Disease. Am. J. Med. 2015;128:229–238. doi: 10.1016/j.amjmed.2014.10.014. - DOI - PMC - PubMed

LinkOut - more resources