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Editorial
. 2018 Aug;30(8):1670-1671.
doi: 10.1105/tpc.18.00593. Epub 2018 Aug 10.

Heat Trims the Fat: HIL1 Functions in Lipid Homeostasis

Christian Danve M Castroverde  1   2
Affiliations
Editorial

Heat Trims the Fat: HIL1 Functions in Lipid Homeostasis

Christian Danve M Castroverde. Plant Cell. 2018 Aug.
No abstract available

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Figures

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The novel heat-induced lipase HIL1 is important for lipid homeostasis and plant thermotolerance. (A) HIL1 contains important domains associated with chloroplastic lipases: a cTP, a membrane-targeting C2 domain, and a lipase-like domain. In vitro studies confirmed the enzymatic function of HIL1 in the catabolism of glycerolipids with polyunsaturated acyl groups, like MGDG. (B) Functional characterization of the hil1 T-DNA insertion mutant line indicated that this protein is important for acquired thermotolerance and lipid remodeling after heat stress (38°C for 2 h followed by 45°C for 3 h). Compared with the wild type (WT), hil1 mutants are indistinguishable at control temperatures but have phenotypic differences after an elevated temperature regime. Complementation with a normal HIL1 allele (lines #3, #6, and #9) rescues the bleached mutant phenotype. (Adapted from Higashi et al. [2018], Figures 2A and 4D.)
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References

    1. Higashi Y., Okazaki Y., Myouga F., Shinozaki K., Saito K. (2015). Landscape of the lipidome and transcriptome under heat stress in Arabidopsis thaliana. Sci. Rep. 5: 10533. - PMC - PubMed
    1. Higashi Y., Okazaki Y., Takano K., Myouga F., Shinozaki K., Knoch E., Fukushima A., Saito K. (2018). HEAT INDUCIBLE LIPASE1 remodels chloroplastic monogalactosyldiacylglycerol by liberating α-linolenic acid in Arabidopsis leaves under heat stress. Plant Cell 30: 1887–1905. - PMC - PubMed

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