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. 2018 Jul 27:12:1355-1361.
doi: 10.2147/PPA.S151838. eCollection 2018.

Bipolar disorder and adherence: implications of manic subjective experience on treatment disruption

Samuel Bulteau  1   2 , Marie Grall-Bronnec  1   2 , Pierre-Yves Bars  3 , Edouard-Jules Laforgue  1 , François Etcheverrigaray  4 , Jean-Christophe Loirat  3 , Caroline Victorri-Vigneau  2   4 , Jean-Marie Vanelle  1 , Anne Sauvaget  1
Affiliations

Bipolar disorder and adherence: implications of manic subjective experience on treatment disruption

Samuel Bulteau et al. Patient Prefer Adherence. .

Abstract

Objective: Therapeutic observance is one of the cornerstones of bipolar disease prognosis. Nostalgia of previous manic phase has been described as a cause of treatment retrieval in bipolar disorder. But to date no systematic study has examined manic episode remembering stories. Our aim was to describe manic experience from the patient's point of view and its consequences on subjective relation to care and treatment adherence.

Patients and methods: Twelve euthymic patients with bipolar I disorder were interviewed about their former manic episodes and data was analyzed, thanks to a grounded theory method.

Results: Nostalgia was an anecdotal reason for treatment retrieval in bipolar I disease. Although the manic experience was described as pleasant in a certain way, its consequences hugely tarnish the memory of it afterward. Treatment interruption appears to be mostly involuntary and state-dependent, when a euphoric subject loses insight and does not see any more benefit in having treatment.

Conclusion: Consciousness destructuring associated with mood elation should explain treatment disruption in bipolar I patients more than nostalgia. Taking a manic episode story into account may help patients, family, and practitioners to achieve better compliance by improving their comprehension and integration of this unusual experience.

Keywords: compliance; insight; mania; nostalgia; psychoeducation.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

References

    1. Cerimele JM, Chwastiak LA, Dodson S, Katon WJ. The prevalence of bipolar disorder in general primary care samples: a systematic review. Gen Hosp Psychiatry. 2014;36(1):19–25. - PMC - PubMed
    1. Tsai SM, Chen C, Kuo C, Lee J, Lee H, Strakowski SM. 15-year outcome of treated bipolar disorder. J Affect Disord. 2001;63(1–3):215–220. - PubMed
    1. Levin J, Tatsuoka C, Cassidy K, Aebi M, Sajatovic M. Trajectories of medication attitudes and adherence behavior change in non-adherent bipolar patients. Compr Psychiatry. 2015;58:29–36. - PMC - PubMed
    1. Col SE, Caykoylu A, Karakas Ugurlu G, Ugurlu M. Factors affecting treatment compliance in patients with bipolar I disorder during prophylaxis: a study from Turkey. Gen Hosp Psychiatry. 2014;36(2):208–213. - PubMed
    1. Chang C-W, Sajatovic M, Tatsuoka C. Correlates of attitudes towards mood stabilizers in individuals with bipolar disorder. Bipolar Disord. 2015;17(1):106–112. - PMC - PubMed

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