Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Jul 30;8(3):e2018032.
doi: 10.4322/acr.2018.032. eCollection 2018 Jul-Sep.

Perioperative myocardial infarction: diagnostic clues and prevention

Affiliations
Case Reports

Perioperative myocardial infarction: diagnostic clues and prevention

Larry Nichols. Autops Case Rep. .

Abstract

The diagnosis of perioperative myocardial infarction can be missed if the pain is masked by postoperative analgesia and the possibility is not considered. This report is the case of a patient with a missed diagnosis of perioperative myocardial infarction. Myocardial injury and infarction from noncardiac surgery is currently the subject of intense interest and research. This report illustrates the importance of the diagnosis and suggests clues that can be used to make the diagnosis.

Keywords: Autopsy; Cognitive dysfunction; Diagnostic errors; General surgery; Myocardial infarction.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None

Figures

Figure 1
Figure 1. The dead cardiac myocytes (all but lower right corner) show hypereosinophilia and loss of nuclei, associated with an infiltrate of degenerating neutrophils, many of which have lysed, releasing basophilic debris (nuclear dust).
Figure 2
Figure 2. The apparent gaps in this luminal thrombosis are due to artefactual tissue folding, particularly around two calcifications, one of which has been pushed out of the tissue section by the microtome blade.

Similar articles

References

    1. Botto F, Alonso-Coello P, Chan MT, et al. . Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes. Anesthesiology. 2014;120(3):564-78. 10.1097/ALN.0000000000000113. - DOI - PubMed
    1. Devereaux PJ, Biccard BM, Sigamani A, et al. . Association of postoperative high-sensitivity troponin levels with myocardial injury and 30-day mortality among patients undergoing noncardiac surgery. JAMA. 2017;317(16):1642-51. 10.1001/jama.2017.4360. - DOI - PubMed
    1. George R, Menon VP, Edathadathil F, et al. . Myocardial injury after noncardiac surgery—incidence and predictors from a prospective observational cohort study at an Indian tertiary care centre. Medicine. 2018;97(19):e0402. 10.1097/MD.0000000000010402. - DOI - PMC - PubMed
    1. Abbott TEF, Pearse RM, Archbold RA, et al. . Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery. Br J Anaesth. 2017;119(1):78-86. 10.1093/bja/aex165. - DOI - PubMed
    1. Devereaux PJ, Mrkobrada M, Sessler DI, et al. . Aspirin in patients undergoing noncardiac surgery. N Engl J Med. 2014;370(16):1494-503. 10.1056/NEJMoa1401105. - DOI - PubMed

Publication types