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Comment
. 2018 Aug;19(8):e377.
doi: 10.1016/S1470-2045(18)30517-5.

Sex as a predictor of response to cancer immunotherapy

Brian Claggett  1 , Lu Tian  2 , Zachary R McCaw  3 , Masahiro Takeuchi  4 , Lee-Jen Wei  5
Affiliations
Comment

Sex as a predictor of response to cancer immunotherapy

Brian Claggett et al. Lancet Oncol. 2018 Aug.
No abstract available

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Conflict of interest statement

We declare no competing interests.

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References

    1. Conforti F, Pala L, Bagnardi V, et al. Cancer immunotherapy efficacy and patients’ sex: a systematic review and meta-analysis. Lancet Oncol 2018; 19: 737–46. - PubMed
    1. Uno H, Claggett B, Tian L, et al. Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis. J Clin Oncol 2014; 32: 2380–85. - PMC - PubMed
    1. Pak K, Uno H, Kim DH, et al. Interpretability of cancer clinical trial results using restricted mean survival time as an alternative to the hazard ratio. JAMA Oncol 2017; 3: 1692–96. - PMC - PubMed
    1. Alexander BM, Schoenfeld JD, Trippa L. Hazards of hazard ratios-deviations from model assumptions in immunotherapy. N Engl J Med 2018; 378: 1158–59. - PubMed
    1. Hasegaw T, Claggett B, Tian L, Solomon SD, Pfeffer MA, Wei LJ. The myth of making inferences for an overall treatment efficacy with data from multiple comparative studies via meta-analysis. Stat Biosci 2017; 9: 284–97.

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