Application of ultrasonography in the diagnosis and treatment of cesarean scar pregnancy

Abstract

The morbidity of cesarean scar pregnancy (CSP) has shown an obvious ascending tendency with the increase of cesarean delivery in China and other countries. The timely diagnosis and treatment of CSP currently relies on medical imaging technology. In this article, we analyzed and compare the imaging methods in diagnosis of CSP. The imaging methods to diagnose CSP include traditional two-dimensional color/power Doppler ultrasound (2D-US), three-dimensional color/power Doppler ultrasound (3D-US), contrast-enhanced ultrasound (CEUS), and Magnetic Resonance Imaging (MRI). 2D-US provides important information including the location and size of gestational sac (GS), embryo with or without heart activity, and the relationship between the GS and scar. It can also divide CSP into different types, which are convenient for the choice of clinical treatment. CEUS can observe the perfusion of CSP in real-time, the arrival time of GS in CSP is earlier than that of the myometrium. It provides reliable evidence for diagnosis and evaluation of the treatment of CSP, which is helpful for making treatment plans and post-treatment follow-up. Combined use of ultrasound and CEUS could be a problem-solving method for CSP when conventional ultrasound is often inconclusive. Ultrasound has been accepted as the first-line imaging method and an important guiding method for CSP, supervising local methotrexate injection and curettage.

Keywords: Cesarean scar pregnancy (CSP); Contrast-enhanced ultrasound (CEUS); Doppler ultrasound; Transvaginal ultrasound (TVS); Ultrasonography.