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Case Reports
. 1977 Apr;20(3):887-94.
doi: 10.1002/art.1780200319.

Chronic polyarthritis associated with hypogammaglobulinemia. A study of two patients

A I Grayzel, R Marcus, R Stern, R J Winchester
Case Reports

Chronic polyarthritis associated with hypogammaglobulinemia. A study of two patients

A I Grayzel et al. Arthritis Rheum. 1977 Apr.

Abstract

Two adult patients with hypogammaglobulinemia and chronic synovitis were studied. Synovial tissue and fluid were examined by histologic, virologic, and immunologic methods. The synovium lacked characteristic histologic features of rheumatoid arthritis, and B lymphocytes were absent from the synovial tissue, fluid, and peripheral blood. These 2 patients may represent a form of chronic synovitis produced in the absence of any B lymphocyte response.

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