Disseminated immune deposits in lupus erythematosus
- PMID: 301037
- DOI: 10.1002/art.1780200408
Disseminated immune deposits in lupus erythematosus
Abstract
Immunohistologic studies were performed on autopsy tissues of 2 patients with systemic lupus erythematosus. All tissues examined--the kidney, lung, spleen, liver, intestine, peritoneum, and choroid plexus--contained immune deposits. Antinuclear antibody concentration in immunoglobulin G eluted from lung and spleen tissue was higher than in serum immunoglobulin G. These findings support the assumption that in systemic lupus erythematosus the renal as well as the extrarenal lesions can be attributed to vascular deposition of immune complexes.
Similar articles
-
Host immunoglobulin G and complement deposits in the choroid plexus during spontaneous immune complex disease.Science. 1973 Apr 27;180(4084):408-10. doi: 10.1126/science.180.4084.408. Science. 1973. PMID: 4267048
-
Immunoglobulin G deposits in the choroid plexus of a child with systemic lupus erythematosus.J Pediatr. 1974 Sep;85(3):385-7. doi: 10.1016/s0022-3476(74)80125-3. J Pediatr. 1974. PMID: 4610421 No abstract available.
-
Experimental chronic serum sickness in rabbits that received daily multiple and high doses of antigen: a systemic disease.Ann N Y Acad Sci. 1975 Jun 30;254:603-13. doi: 10.1111/j.1749-6632.1975.tb29207.x. Ann N Y Acad Sci. 1975. PMID: 1101784 No abstract available.
-
Immune complex deposits in the choroid plexus.Birth Defects Orig Artic Ser. 1978;14(5):237-44. Birth Defects Orig Artic Ser. 1978. PMID: 150870 No abstract available.
-
Immunological diagnosis of rheumatoid arthritis and systemic lupus erythematosus.Ann Clin Res. 1975 Jun;7(3):168-82. Ann Clin Res. 1975. PMID: 1103712 Review. No abstract available.
Cited by
-
Deposition of circulating antigen--antibody complexes in the gastrointestinal tract of rabbits with chronic serum sickness.Am J Dig Dis. 1978 Dec;23(12):1098-106. doi: 10.1007/BF01072885. Am J Dig Dis. 1978. PMID: 367154
-
Systemic lupus erythematosus and pulmonary manifestation.Ann Rheum Dis. 1980 Aug;39(4):414-5. doi: 10.1136/ard.39.4.414-b. Ann Rheum Dis. 1980. PMID: 7436570 Free PMC article. No abstract available.
-
Complement and Humoral Adaptive Immunity in the Human Choroid Plexus: Roles for Stromal Concretions, Basement Membranes, and Epithelium.J Neuropathol Exp Neurol. 2016 May;75(5):415-28. doi: 10.1093/jnen/nlw017. Epub 2016 Mar 19. J Neuropathol Exp Neurol. 2016. PMID: 26994633 Free PMC article.
-
Pulmonary renal syndromes. II. Etiology and pathogenesis.Yale J Biol Med. 1982 Jan-Feb;55(1):11-26. Yale J Biol Med. 1982. PMID: 6810558 Free PMC article. Review.
-
Pulmonary hypertension in hydralazine induced systemic lupus erythematosus: association with C4 null allele.Ann Rheum Dis. 1986 Sep;45(9):771-3. doi: 10.1136/ard.45.9.771. Ann Rheum Dis. 1986. PMID: 3767464 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources